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RSSSlow aging by reducing your dietary AGE

Posted on Thu, 16 Jul 09

Slow aging by reducing your dietary AGE

Hidden toxic substances in our diet may lead to accelerated aging.  Substances known as advanced glycation end products (AGE) are present at high concentrations in processed foods, particularly foods that are exposed to unusually high heat such as in industrial ovens or deep frying [1].  Research suggests that the level of AGE in our food may accelerate physiological aging and lead to disease development.

When AGE is digested and absorbed it binds to a cellular receptor called RAGE (analogous to a key [AGE] unlocking a door [RAGE]). When RAGE is triggered it initiates disease processes including inflammation, oxidative stress and cellular dysfunction which may eventually lead to the manifestation of physical disease [2].

Allergy and autoimmune diseases, brain degeneration, heart disease, cancer, diabetes and digestive disorders are just some of the conditions thought to be linked to dietary AGE [3].

Avoiding fast, processed and fried foods and returning to traditional methods of cooking such as boiling and stewing can reduce the AGE content of your diet by up to 50% [1].  Also, cooking with plenty of herbs and spices which are naturally high in antioxidants may help reduce the AGE of your food [4].  There is evidence to suggest that reducing the AGE of your diet may improve your health and reduce your risk of life threatening disease [5].

References

1. Goldberg T et al. Advanced Glycoxidation End Products in Commonly Consumed Foods. J Am Diet Assoc. 2004;104:1287-1291.

2. Uribarri J et al. Diet-derived advanced glycation end products are major contributors to the body's AGE pool and induce inflammation in healthy subjects.Ann N Y Acad Sci. 2005 Jun;1043:461-6.

3. Bengmark S. Advanced Glycation and Lipoxidation End Products–Amplifiers of Inflammation: The Role of Food. Journal of Parenteral and Enteral Nutrition, Vol. 31, No. 5, 430-440 (2007).

4. Wu CH, Yen GC. Inhibitory effect of naturally occurring flavonoids on the formation of advanced glycation endproducts. J Agric Food Chem. 2005 Apr 20;53(8):3167-73.

5. Yamagishi S, Ueda S, Okuda S. Food-derived advanced glycation end products (AGEs): a novel therapeutic target for various disorders. Curr Pharm Des. 2007;13(27):2832-6

Tags: Aging, Diet, Nutrition, AGE, Chronic Disease

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Comments (7)


Here's a list of AGE contents of foods from the first reference in this article.
Posted by JLL (http://inhumanexperiment.blogspot.com) on Wed, 2 Sep 09 - 12:00am


I guess links in comments are not allowed... well the correct link is next to my name.
Posted by JLL (http://inhumanexperiment.blogspot.com/2009/09/age-content-of-foods.html) on Wed, 2 Sep 09 - 12:00am


Aging can be scary thing for everyone, everyone want to push it as much as possible. I have started using Proleva which uses Resveratrol which is found in skin of the red grapes helps in slow aging by increasing life span. From the time I started using Proleva I have seen excellent results. Better energy, good sleep and lots of good health.
Posted by Chin on Sat, 26 Jun 10 - 12:00am


I agree that since I've started eating a diet rich in seafood and olive oil (similar to the Mediterranean diet) I've felt better than I have in years. Are there any long term studies on this that can verify the results?
Posted by Bill (http://www.articledashboard.com/Article/Healthy-Tips-For-Senior-Citizens/1686560) on Tue, 13 Jul 10 - 12:00am


I have a patient who is 80 but looks like she could be 150 years old and a 90 year old who could be with 60 year old people and they wouldn't know. Genes are very important and research has shown that resveratrol activates the gene 31 which is responsible for healthy cell aging and metabolism. I think I will be recommending revup31 to the 80 year old.
Posted by revup31 (http://www.revup31.co.uk/revup31blog) on Thu, 29 Jul 10 - 12:00am


Couldn't agree more. It's simple logic really- a diet high in antioxidants, essential fatty acids, minerals and vitamins is going to improve health at a cellular level. A diet rich in processed carbs will lead to crash and burn for all organs at some level.
Posted by Republicofskin (http://www.blog.republicofskin.com) on Mon, 9 Aug 10 - 12:00am


Ive noticed green teas work very well. They help give you more energy as well as flushing your system.
Posted by basil matthews ref diet pills (http://dietpillsweight.co.uk/) on Sun, 15 Aug 10 - 12:00am


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